Pantostad 40 CAP

Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production.

Pack size Box of 14 capsules/28 capsules. Bottle of 28 capsules.
Shelf-life 24 months
Composition Panoprazole
Dosage forms and strengths Hard gelatin capsule: 40 mg
Product Code :

Prescribing Information

Indications, usage, dosage and administration

Indications:

  • Gastro-oesophageal reflux disease (GORD).
  • Peptic ulcer disease.
  • Prophylaxis for NSAID-associated ulceration.
  • Pathological hypersecretory states (Zollinger-Ellison syndrome).

Dosage:

  • Gastro-oesophageal reflux disease (GERD): 20 – 40 mg once daily x 4 – 8 weeks. Maintenance therapy: 20 to 40 mg daily. Recurring therapy: 20 mg daily.
  • Peptic ulcer disease:
  • 40 mg once daily x 2 – 4 weeks (duodenal ulceration) or 4 – 8 weeks (benign gastric ulceration).
  • For the eradication of Helicobacter pylori: Pantoprazole (40 mg twice daily) + clarithromycin (500 mg twice daily) + amoxicillin (1 g twice daily) or metronidazole (400 mg twice daily).
  • Prophylaxis for NSAID-associated ulceration: 20 mg daily.
  • Zollinger-Ellison syndrome: The initial dose is 80 mg daily, adjusted as required, up to 240 mg daily. Daily doses greater than 80 mg should be given in 2 divided doses.
  • Hepatic impairment: Reduce dosage (maximum 20 mg daily) or use on alternate days (40 mg daily).
  • Renal impairment: A maximum dose of 40 mg daily.

Usage:

Administered orally. Once-daily doses should be taken in the morning.

Contraindications

Known hypersensitivity to any other ingredient in the formulation.

Adverse reactions

Diarrhoea, hyperglycemia, headache, abdominal pain, liver function tests abnormalities.

Precautions

  • Symptomatic response to therapy with pantoprazole does not preclude the presence of gastric neoplasm.
  • Mild, transient elevations of serum ALT (SGPT).
  • Pantoprazole may lead to malabsorption of cyanocobalamin.
  • Safety and efficacy in children younger than 18 years of age have not been established.
  • Pregnant and nursing women (discontinue nursing or the drug).
  • Driving/ operating machines.