Methylprednisolone is a synthesis glucocorticoid, often used as an esterified or not esterified to treat the diseases that corticosteroid indicated.
|Pack size||Box of 30 tablets, 50 tablets, 100 tablets. Bottle of 100 tablets.|
|Dosage forms and strengths||Tablet: 4 mg|
An anti-inflammatory or immunosuppressive treatment for some diseases including causes due to hematology, allergies, arthritis, cancer and autoimmune.
Adult: initial dosage from 2 – 60 mg daily in 4 divided doses.
Children: based on the severity of the disease and the response, after a satisfactory response is obtained, dosage should be decreased in small decrements to the lowest level that maintains adequate clinical response.
When long-term use: consider an alternate day dosage regimen, then withdrawn gradually.
Contact dermatitis: 24 mg (6 tablets of 4 mg) for the first day, then tapered by 4 mg daily until 21 tablets have been administered for 6 days (6, 5, 4, 3, 2, 1 is the amount of tablets administered from the first day to the sixth day respectively).
Children < 4 years old (more than 3 exacerbations per year) and children 5 – 11 years old (at least 2 exacerbations per year): 1 – 2 mg/kg/day (maximum 60 mg daily) may be added to existing asthma therapy.
Adults and adolescents (at least 2 exacerbations per year): 40-60 mg daily as a single dose or in 2 divided doses, may be added to low-to-high maintenance dosages in the inhaled corticosteroid and a long-acting inhaled b2-agonist bronchodilator, a short course (usually 3 – 10 days) of oral corticosteroid therapy should be continued until the patient achieves a peak expiratory flow (PEF) of 80% of his or her personal best and until symptoms resolve. Once asthma is well controlled, repeated attempts should be made to reduce the oral corticosteroid dosage.
Stadsone 4 is orally administered.
Known hypersensitivity to any of the active substance or excipients.
Serious infections, except septic shock and tuberculous meningitis.
Viral, fungal, or tubercular skin lesions.
Administration of live virus vaccines.
Most commonly when using methylprednisolone in high doses and long-term therapy: insomnia, nervousness; increased appetite, indigestion; hirsutism; diabetes mellitus; arthralgia; cataracts, glaucoma; epistaxis.
Patients with osteoporosis, newly established anastomoses, psychosis, gastric ulcer, duodenal ulcer, diabetes, hypertension, cardiac insufficiency and growing individuals (children), hepatic failure, renal failure, glaucoma, thyroid disease, cataracts.
Elderly: Should be used cautiously with the smallest possible dose, and for the shortest possible time.
The use of Stadsone 4 in pregnant women requires that the anticipated benefits of the drug should be weighed against possible hazards to the mother and the child. Caution is advised when use Stadasone 4 in nursing women.
Acute adrenal insufficiency may occur with abrupt withdrawal after long-term therapy or with stress.High doses can interference with vaccination.